Table 1

GO regulation definitions
GO ID GO term GO definition
GO:0050789 REGULATION OF A BIOLOGICAL PROCESS Any process that modulates the frequency, rate extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048518 POSITIVE REGULATION OF A BIOLOGICAL PROCESS Any process that activates or increases the frequency extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048519 NEGATIVE REGULATION OF A BIOLOGICAL PROCESS Any process that stops, prevents or reduces the extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.

Gene Ontology definitions of regulation, positive regulation and negative regulation of biological processes.

Mihăilă et al.

Mihăilă et al. BMC Bioinformatics 2013 14:2   doi:10.1186/1471-2105-14-2

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