Effect of using paired-end data using a wgsim synthetic data set. The effect of mapping paired-end reads of length 70 to the Human genome. 1 million reads were used to test RMAP and MAQ while 16 million reads were used to test the other tools. SE and PE refer to single end and paired end, respectively. Error is only provided for PE due to exceeding the allowed insert size mrsFAST is used for the ungapped alignment and mrFAST is used for the gapped one.
Hatem et al. BMC Bioinformatics 2013 14:184 doi:10.1186/1471-2105-14-184