Figure 1.

An example image (left) and corresponding segmentation ground truth (right) from data set [1].‚ÄČIt can be seen that besides the pixel-wise inhomogeneity within a cell nucleus, some cell nuclei exhibit much lower intensities than the others; and although the background looks generally dark, it is indeed highly inhomogeneous, with some fairly bright areas and also a few noisy regions displaying very high intensities.

Song et al. BMC Bioinformatics 2013 14:173   doi:10.1186/1471-2105-14-173
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