Table 2

Sensitivity and specificity before and after family adjustment in simulation study
Sensitivity
SNR 3 4 5 6 7
MAF=0.1 Unadjusted 0.9095 0.9240 0.9773 0.9942 0.9988
Family adjusted 0.7106 0.9114 0.9757 0.9937 0.9987
MAF=0.2 Unadjusted 0.9340 0.9777 0.9946 0.9990 0.9991
Family adjusted 0.8828 0.9698 0.9922 0.9984 0.9997
MAF=0.3 Unadjusted 0.9368 0.9796 0.9925 0.9852 0.9812
Family adjusted 0.8570 0.9733 0.9950 0.9990 0.9991
Specificity
SNR 3 4 5 6 7
MAF=0.1 Unadjusted 0.2867 0.9789 0.9946 0.9990 0.9999
Family adjusted 0.9411 0.9864 0.9961 0.9993 0.9999
MAF=0.2 Unadjusted 0.8975 0.9591 0.9776 0.8582 0.6295
Family adjusted 0.9468 0.9740 0.9917 0.9981 0.9997
MAF=0.3 Unadjusted 0.9353 0.9800 0.9919 0.9812 0.9760
Family adjusted 0.8991 0.9684 0.9927 0.9984 0.9990
Overall accuracy
SNR 3 4 5 6 7
MAF=0.1 Unadjusted 0.5253 0.9707 0.9838 0.9878 0.9888
Family adjusted 0.9274 0.9697 0.9838 0.9878 0.9888
MAF=0.2 Unadjusted 0.9244 0.9704 0.9620 0.8996 0.7848
Family adjusted 0.9152 0.9708 0.9915 0.9980 0.9997
MAF=0.3 Unadjusted 0.8761 0.9709 0.9895 0.9809 0.9761
Family adjusted 0.8282 0.9545 0.9896 0.9977 0.9987

Chu et al.

Chu et al. BMC Bioinformatics 2013 14:157   doi:10.1186/1471-2105-14-157

Open Data