|xMSanalyzer doubles the number of features detected in human patient population|
|Parameter||AE column||C18 column|
|MMCD: 2412||MMCD: 1556|
|3,0.3 υ 3,0.8||15955||9396|
|(xMSanalyzer)||MMCD: 5579||MMCD: 2819|
Dialysis patients are highly susceptible to environmental chemicals due to repeated exposures to pharmaceuticals, water, and plastics during dialysis sessions. A dataset from 10 plasma samples collected in dialysis patients, each with 2 analytical replicates, were analyzed by xMSanalyzer (at min.exp = 2) and resulted in a >2-fold increase in feature detection (from 6538 to 15955 features on the AE column), in which most m/z are unmatched in the metabolomics database MMCD.
Uppal et al.
Uppal et al. BMC Bioinformatics 2013 14:15 doi:10.1186/1471-2105-14-15