Table 6

A comparison of MetaCyc (M) and KEGG (K) reaction attributes, for those attributes where one hundred or more objects have a value for that attribute
MetaCyc KEGG
Attribute (M) Frequency (M) Attribute (K) Frequency (K)
Physiologically-Relevant? 10262
Creation-Date 10247
Rpair 8292
Creator 8090
EC-Number 7998 Enzyme 7632
Reaction-Direction 6660
Orphan? 5967
Credits 2779
Rxn-Locations 282
Spontaneous? 238

Attributes are sorted based on the MetaCyc frequency column. Attribute Physiologically-Relevant? describes whether a reaction occurs in vivo. Reaction-Direction specifies the directionality of the reaction. Orphan? is true when no nucleotide or amino-acid sequence has been determined for any enzyme catalyzing this reaction [39,40]. Rxn-Locations specifies the cellular locations in which a reaction occurs (e.g., cytoplasm or mitochondrion). Spontaneous? specifies whether a reaction occurs spontaneously in living organisms and therefore requires no enzyme. KEGG reaction attribute data are derived from the KEGG REACTION dataset, and thus include glycan reactions.

Altman et al.

Altman et al. BMC Bioinformatics 2013 14:112   doi:10.1186/1471-2105-14-112

Open Data