Comparison of our method, IG, FSWeight, and CD-Dist for assessing the reliability of interactions in term of functional homogeneity and localization coherence. The comparison is performed by using data on 12934 interactions from the Krogan Lab Interactome Database [43-45]. (a) Functional homogeneity. (b) Localization coherence. The vertical axis is the proportion of interacting protein pairs which share a common function or cellular localization. The horizontal axis is the coverage of the PPI network comparing the original network.
Lei et al. BMC Bioinformatics 2012 13(Suppl 7):S3 doi:10.1186/1471-2105-13-S7-S3