Figure 10.

Modeling the interactions of Alzheimer-related genes from the fiber pathways. Yellow nodes (AKT1, CASP3, CYCS, GRIA1, GRIN1, and GSK3B) represent the proteins related to the amyloid precursor protein (APP). Red nodes (AR, PRKCZ, CTNNB1, PSEN1, CASP8, and CASP9) represent the proteins that interact with three APP-related proteins (KT1, CASP3, CYCS, GRIA1, GRIN1, and GSK3B). Green nodes represent the proteins that interact with two proteins among APP, AKT1, CASP3, CYCS, GRIA1, GRIN1, and GSK3B. The remaining nodes represent the proteins that interact with the APP-related proteins only. Detailed information of the proteins is available in Additional file 1.

Park et al. BMC Bioinformatics 2012 13(Suppl 7):S10   doi:10.1186/1471-2105-13-S7-S10