Plate model for Robust Mixture. Our Mixture Model for robust estimation of PSI and coverage of cassette junctions from RNA-seq data. Only the read counts at each position (shaded xp) are observed. The mixture components (mp), robust expression estimates for each junction (λie), and the overall cover (C) and percent-spliced-in (Ψ) are inferred by the model.
Kakaradov et al. BMC Bioinformatics 2012 13(Suppl 6):S11 doi:10.1186/1471-2105-13-S6-S11