Table 3

Ten most conserved inter-residue contacts.

CRkl

Receptor

Ligand

Distance (Å)


T25

0,173

TYR

35

TYR

999

3,48

0,167

PHE

51

ASP

996

5,82

0,163

PHE

51

ILE

1053

4,00

0,150

ASN

52

ASP

996

3,84

0,147

THR

44

TYR

999

2,60

0,140

ASN

52

TYR

999

4,20

0,140

ILE

46

ILE

997

3,65

0,137

THR

45

TYR

999

3,49

0,133

ILE

49

GLN

1035

6,09

0,130

ILE

49

ILE

995

5,29


T26

0,232

GLU

293

GLU

116

3,62

0,210

GLU

293

THR

114

2,66

0,197

PHE

424

PRO

115

3,43

0,190

ALA

249

GLU

116

2,92

0,187

SER

205

GLU

116

2,66

0,174

PHE

424

GLU

116

5,55

0,174

HIS

246

GLU

116

2,79

0,168

MET

204

GLU

116

3,75

0,158

GLN

336

THR

114

2,94

0,158

GLY

248

GLU

116

3,94


T29

0,069

TRP

236

PHE

165

7,67

0,063

HIS

221

PHE

165

3,65

0,063

VAL

195

ARG

195

6,53

0,060

TRP

236

GLU

204

3,03

0,057

PHE

231

PRO

236

3,88

0,057

LYS

223

THR

200

5,73

0,054

VAL

195

PHE

165

7,28

0,051

PHE

231

LEU

237

3,35

0,051

TRP

236

TYR

207

3,67

0,051

VAL

233

THR

200

6,82


T32

0,223

LEU

126

TYR

87

3,71

0,200

GLY

127

TYR

87

3,74

0,183

SER

125

TYR

87

7,68

0,169

GLY

100

TYR

87

4,03

0,160

ASN

62

TYR

87

9,91

0,157

SER

128

TYR

87

3,49

0,146

ASN

62

THR

89

4,65

0,143

ASN

155

THR

89

4,56

0,140

LEU

96

TYR

87

3,52

0,137

GLY

127

LEU

91

3,51


The ten most conserved inter-residue contacts are reported for targets T25, T26, T29 and T32, together with corresponding distances in the native structures [36-39]. Distances above 5 Å are outlined in bold.

Vangone et al. BMC Bioinformatics 2012 13(Suppl 4):S19   doi:10.1186/1471-2105-13-S4-S19

Open Data