Table 1

Kinetic Parameters for the in silico Ribocell model at room temperature.

Kinetic

Parameters

Values

Process Description

Ref.


kSS[s-1M-1]

8.8·106

Formation of dimers RcRP and RcRL

[28]

kS[s-1]

2.2·10-6

Dissociation of dimers RcRP and RcRL

[28]

kR@S[s-1M-1]

5.32·105

Formation of R@S

[29]

kR@SS[s-1]

9.9·10-3

Dissociation of Complexes R@ScS

[29]

kNTP[s-1M-1]

0.113

Nucleotide Polymerization in Oleic Vesicle

[31]

kL [s-1M-1]

1.7·103

Lipid Precursor Conversion*

[30]

kin [dm2s-1]

7.6·1019

Oleic acid association to the membrane

[26]

kout [dm2s-1]

7.6·10-2

Oleic acid release from the membrane

[26]

PP [cm·s-1]

4.2 10-9

Membrane Permeability to Lipid Precursor

PNTP [cm·s-1]

1.9 10-11

Membrane Permeability to Nucleotides

[31]

PW = PS

0.0

Membrane Permeability to W and genetic staff

Paq[cm·s-1]

1.0·10-3

Oleic Acid Membrane Permeability to Water

[32]


*kL is 105 times larger than the value of the splicing reaction, catalyzed by the hammerhead ribozyme.

Mavelli BMC Bioinformatics 2012 13(Suppl 4):S10   doi:10.1186/1471-2105-13-S4-S10

Open Data