Table 1

Comparison of modRP results to control studies

Lind, et al., Published Results

Our Results, Corrected Threshold: 6.54E-08


    SNP

    p-value

    SNP

    Fisher

    Mod Fisher

    RP

    Mod RP


    Australian (Pos Control)


rs7530302

1.90E-09

AD/ND Comorbidity

rs7530302

5.29E-08

2.33E-07

5.60E-08

3.39E-08


rs1784300

2.60E-09

rs1784300

1.19E-09

2.00E-09

6.00E-09

3.57E-09


rs12882384

4.86E-08

rs12882384

2.16E-07

5.51E-07

1.08E-07

5.72E-08


    Aus/Dutch (Neg Control)


rs2247219

6.23E-06

AD/AD/AD Meta

rs2247219

2.22E-05

2.02E-05

1.52E-05

1.41E-05


rs6705087

4.80E-06

ND/ND Meta

rs6705087

1.16E-05

1.12E-05

4.02E-06

5.64E-06


N/A

AD/ND/AD/AD/ND Co

rs1784300

3.31E-08

2.20E-08

1.05E-07

1.27E-07


Yu, et al., Published Results

Our Results, corrected Threshold: 8.88E-06


    SNP

    p-value

Single Phenotypes (Neg)

    SNP

    Fisher

    Mod Fisher

    RP

    Mod RP


rs1938584

3.00E-03

Cocaine

rs1476880

1.36E-04

1.41E-04

1.32E-04

1.41E-04


rs1516003

9.00E-04

Opium

rs1333962

1.80E-02

1.16E-05

1.01E-05

1.15E-05


rs769592

2.00E-03

Nicotine

rs2194

4.20E-02

3.48E-04

3.47E-04

3.47E-04


rs1937443

4.00E-03

Alcohol

rs6505380

1.30E-05

1.37E-04

1.48E-04

1.37E-04


Comparison of Lind and Yu results with results from our four tested methods. Tests that satisfied the Bonferroni correction threshold are in bold.

McEachin et al. BMC Bioinformatics 2012 13(Suppl 2):S8   doi:10.1186/1471-2105-13-S2-S8

Open Data