The Ensemble Method. The Ensemble Method: An example with 4 chromosomes each with an orientation and a distinct color above. (i) The chromosomes are first arranged as a circular ring. (ii) Then they are randomly permuted and randomly flipped. Then a random cut is placed on the ring, shown as a dashed line. (iii) Then the ring is flattened out and is staged as input to the IRiS pipeline.
Utro et al. BMC Bioinformatics 2012 13(Suppl 19):S17 doi:10.1186/1471-2105-13-S19-S17