Precision of relative protein quantifications. (a) Study of breast cancer cell lines, protein SLC44A2. (b) Study of subjects with osteosarcoma, Entrez ID 28299. X-axis: condition. Y-axis: model-based estimate of log-abundance. Vertical lines are the 95% confidence intervals. Solid black lines: protein quantification based on the proposed joint modeling of all conditions. Dashed green lines: protein quantification based on the naïve analysis, which averages feature intensities in each replicate. The proteins are the same as in Figure 3.
Clough et al. BMC Bioinformatics 2012 13(Suppl 16):S6 doi:10.1186/1471-2105-13-S16-S6