Table 3

Enrichment Analysis of Breast Cancer Related Markers

PathwayID

PathwayName

N

P-value

AE

RE

MJI


hsa05212

Pancreatic cancer

72

3.74E-08

7

75.59

0.2819

hsa05213

Endometrial cancer

53

1.07E-07

6

88.02

0.2566

hsa05215

Prostate cancer

100

1.07E-07

7

54.43

0.2683

hsa05223

Non-small cell lung cancer

60

1.60E-07

6

77.75

0.25

hsa05218

Melanoma

72

3.55E-07

6

64.79

0.2417

hsa05200

Pathways in cancer

348

1.02E-06

9

20.11

0.3129

hsa05219

Bladder cancer

42

1.02E-06

5

92.56

0.2262

h_RacCycDPathway

Influence of Ras and Rho proteins on G1 to S Transition

26

6.66E-06

4

119.62

0.2103

hsa05214

Glioma

69

6.66E-06

5

56.34

0.2029

hsa05220

Chronic myeloid leukemia

74

7.91E-06

5

52.54

0.2005

hsa05166

HTLV-I infection

272

1.71E-05

7

20.01

0.2462

hsa05222

Small cell lung cancer

90

1.71E-05

5

43.2

0.1944

200124

E-cadherin signaling in the nascent adherens junction

39

2.10E-05

4

79.75

0.1846

200141

FOXM1 transcription factor network

41

2.37E-05

4

75.86

0.1821

200190

a6b1 and a6b4 Integrin signaling

46

3.40E-05

4

67.61

0.1768

hsa04110

Cell cycle

124

5.80E-05

5

31.35

0.1868

hsa05210

Colorectal cancer

62

8.23E-05

4

50.16

0.1656

200041

Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

80

1.67E-05

4

38.88

0.1583


DiseaseID

DiseaseName

N

P-value

AE

RE

MJI


MESH:D002528

Cerebellar Neoplasms

332

6.34E-07

9

32.39

0.3136

MESH:D020967

Myotonic Disorders

278

1.87E-05

7

30.09

0.2459

MESH:D042883

Choledocholithiasis

157

1.87E-05

6

45.67

0.2191

MESH:D002282

Adenocarcinoma, Bronchiolo-Alveolar

339

3.44E-05

7

24.68

0.2437

MESH:D009134

Muscular Atrophy, Spinal

1119

3.44E-05

11

11.75

0.3716

MESH:D016510

Corneal Neovascularization

669

3.44E-05

9

16.08

0.3067

MESH:D044483

Intestinal Polyposis

120

4.42E-05

5

49.79

0.1875

PA443756

Colonic Neoplasms

122

4.42E-05

5

48.98

0.1872

PA445062

Neoplasms

237

4.42E-05

6

30.25

0.2127

MESH:D007972

Leukoplakia, Oral

238

4.42E-05

6

30.13

0.2126

MESH:D003123

Colorectal Neoplasms, Hereditary Nonpolyposis

126

4.42E-05

5

47.42

0.1865

MESH:D046152

Gastrointestinal Stromal Tumors

148

8.01E-05

5

40.37

0.1836


DrugID

DrugName

N

P-value

AE

RE

MJI


PA451581

tamoxifen

74

1.83E-03

5

18.03

0.2124

PA131301952

gefitinib

39

1.83E-03

4

27.36

0.1941

PA152241907

lapatinib

14

1.83E-03

3

57.17

0.2143

PA449383

docetaxel

77

9.81E-03

4

13.86

0.1688

PA449509

estrogens

79

9.89E-03

4

13.51

0.1682


OrganID

OrganName

N

P-value

AE

RE

MJI


larynx

larynx

88

1.97E-2

2

25.45

0.2114


Zhang and Drabier BMC Bioinformatics 2012 13(Suppl 15):S7   doi:10.1186/1471-2105-13-S15-S7

Open Data