Influence of duplication age on sensitivity. This histogram shows the distribution of tandem gene unit pairs (in grey) and the associated proportion of tandem unit pairs detected by ReD Tandem (in black) as a function of the evolutionary distance as estimated by dS. As expected for a DNA based analysis, ReD Tandem is able to recover a large fraction of recently duplicated genes but is less efficient for older duplications.
Audemard et al. BMC Bioinformatics 2012 13:83 doi:10.1186/1471-2105-13-83