Power values and error rates. (A) and (C) show the actual FDR for the FDRS and the FNS design, respectively, (B) and (D) the corresponding mean number of rejected alternatives for n1=6, n2=12, α=0.05, m = 1000, π0 = 0.99, ms = 6. The effect sizes are Δ = 1 (solid line) or Δ = 1.6 (dotted line). The integrated approach is depicted in black, the pilot approach in grey (50000 simulation runs per scenario).
Zehetmayer and Posch BMC Bioinformatics 2012 13:81 doi:10.1186/1471-2105-13-81