Computational resources. Both Atlas-SNP2 (a.) and Atlas-Indel2 (b.) were tested on a series of BAM files to evaluate run time and maximum memory usage. The algorithm for both applications is designed so that runtime increases linearly with the number of reads analyzed, while memory usage is approximately constant, based on the size of the reference genome.
Challis et al. BMC Bioinformatics 2012 13:8 doi:10.1186/1471-2105-13-8