Gene ontology enrichment analysis comparing TOM with MI based adjacencies in 8 empirical data sets. 5 best GO enrichment p-values from all modules identified using each adjacency are log transformed, pooled together and shown as barplots. Error bars stand for 95% confidence intervals. On top of each panel is a p-value based on multi-group comparison test. TOM outperforms the others in 5 data sets. ARACNE(ε = 0 ) wins in two data sets, making it the second best.
Song et al. BMC Bioinformatics 2012 13:328 doi:10.1186/1471-2105-13-328