Additional file 11.

Base-calling of human TP53 454 amplicon resequencing data. Percentage of reads with different number of mismatches in the mapping between either HPCall (with or without training) or the native 454 base-caller and the human TP53 gene reference sequence. HPCall results in more perfect-matching reads. When trained on the E. coli data set the percentage of perfect-matching reads decreases slightly.

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Beuf et al. BMC Bioinformatics 2012 13:303   doi:10.1186/1471-2105-13-303