Additional file 10.

Comparison of mapping mismatches. Percentage of reads with different numbers of mismatches in the mapping between the reads produced by either HPCall or the native 454 base-caller and the E. coli K-12 reference sequence. For mapping either ssaha2 or subread is used. Detected number of sequence variants for the E. coli data set using ssahaSNP. HPCall results in more perfect-matching reads and less overall indels and SNPs.

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Beuf et al. BMC Bioinformatics 2012 13:303   doi:10.1186/1471-2105-13-303