The TRN of H. sapiens with a subnetwork related to cancer highlighted. In this subnetwork, external signals (i.e. Growth factors, other proteins and molecules) regulate or affect the proteins c-Myc, FLI1 and ERG. Many other regulatory connections and transcription factors are omitted for simplicity.
Gülsoy et al. BMC Bioinformatics 2012 13:250 doi:10.1186/1471-2105-13-250