Dali Z-scores of SNs of T0604 CASP9 target plotted against their FS values. No correlation between structural and functional similarity of T0604 native structure SNs can be observed; this is the reason for weak performance of GOBA in this case. The red line marks the Z-score 0.95 quantiles calculated for SNs of a representative set of native proteins. The SNs of T0604 violate the pattern acquired from the analysis of native structures.
Konopka et al. BMC Bioinformatics 2012 13:242 doi:10.1186/1471-2105-13-242