A schematic diagram of counting network links and a real example of network links.(A) A simple example of how links are counted between genes in AGS and FGS. The ’x’ symbol indicates a fixed number k of genes; (B) A realistic example of network links between 257 deregulated proteins in a tumor (diamonds) and 10 genes known to be involved in the epithelial-mesenchymal transition (circles). Network nodes without links to the AGS or FGS genes are not shown. The graph is generated using a graphics tool in the FunCoup web site (http://funcoup.sbc.su.se webcite).
Alexeyenko et al. BMC Bioinformatics 2012 13:226 doi:10.1186/1471-2105-13-226