Cognate bias hypothesis I: data retrieved via ANCAC. Relative frequency of amino acids in their biosynthetic* enzymes plotted against their frequency in all protein sequences of the COG database. Each data point represents the relative frequency score calculated from the sequences of one species. Database: COG, organisms: all, sequence features: amino acids, normalization: against all sequences in the selected database, subgrouping: by species.
Meiler et al. BMC Bioinformatics 2012 13:223 doi:10.1186/1471-2105-13-223