Figure 2 .

Synthetic regions. BAF (left graphs) and LRR (right graphs) signals of some example synthetic regions generated with CnaGen at different normal cell contamination levels: a heterozygous deletion (first column), a normal diploid region (second column), the various heterozygous CNA events up to copy number 5 (third to seventh columns) and two concrete cases of 2 and 3-subclone CNAs (last two columns). Each SNP probe provides a measurement of the proportion of one of the alleles (BAF) and the total intensity coming from the two alleles (LRR). Additional file 2 contains the same figure with noiseless data, so that BAF subclone bands can be seen clearly.

Mosén-Ansorena et al. BMC Bioinformatics 2012 13:192   doi:10.1186/1471-2105-13-192
Download authors' original image