Table 1

Protein pairs ranked by the discriminability index scores
Protein 1 (upregulated in IPS progressors) Protein 2 (downregulated in IPS progressors) DI score p-value FDR rate
APCS Serum amyloid P-component HGFAC Hepatocyte growth factor activator 2.01 0 0.00
C8G Complement component C8 gamma chain HGFAC Hepatocyte growth factor activator 1.60 1.6×10−6 0.01
APCS Serum amyloid P-component CFHR1;LOC100293069 Complement factor H-related 1 1.58 1.6×10−6 0.01
C4BPA C4b-binding protein alpha chain ENO2 Gamma-enolase 1.48 6.3×10−6 0.01
C4BPA C4b-binding protein alpha chain HGFAC Hepatocyte growth factor activator 1.45 9.5×10−6 0.01
APOA4 Apolipoprotein A-IV ALB Putative uncharacterized protein ALB 1.44 9.5×10−6 0.01
APCS Serum amyloid P-component CFHR2 Isoform Short of Complement factor H-related protein 2 1.43 1.1×10−6 0.01
F2 Prothrombin (Fragment) HGFAC Hepatocyte growth factor activator 1.37 3.5×10−6 0.03
APOD Apolipoprotein D HGFAC Hepatocyte growth factor activator 1.35 5.7×10−6 0.05
CPB2 Isoform 1 of Carboxypeptidase B2 HGFAC Hepatocyte growth factor activator 1.31 9.3×10−6 0.08
SERPINA6 Corticosteroid-binding globulin HGFAC Hepatocyte growth factor activator 1.30 9.8×10−6 0.09
APCS Serum amyloid P-component F10 Coagulation factor X 1.30 1.1×10−4 0.09
C8A Complement component C8 alpha chain HGFAC Hepatocyte growth factor activator 1.26 1.6×10−4 0.11
APOA4 Apolipoprotein A-IV GPX3 Glutathione peroxidase 3 1.25 1.7×10−4 0.10
APOB Apolipoprotein B-100 HGFAC Hepatocyte growth factor activator 1.24 1.8×10−4 0.10
FGG Isoform Gamma-B of Fibrinogen gamma chain AZGP1 alpha-2-glycoprotein 1, zinc” 1.23 2.0×10−4 0.10
AGT Angiotensinogen HGFAC Hepatocyte growth factor activator 1.22 2.1×10−4 0.10
APCS Serum amyloid P-component ENO2 Gamma-enolase 1.18 2.8×10−4 0.13
CPB2 Isoform 1 of Carboxypeptidase B2 C1QC Complement C1q subcomponent subunit C 1.17 2.9×10−4 0.12
APCS Serum amyloid P-component GPX3 Glutathione peroxidase 3 1.17 3.0×10−4 0.11
C4BPA C4b-binding protein alpha chain LBP Lipopolysaccharide-binding protein 1.16 3.0×10−4 0.11
APCS Serum amyloid P-component LOC653879 similar to complement component 3 1.15 3.3×10−4 0.11
CPB2 Isoform 1 of Carboxypeptidase B2 AFM Afamin 1.15 3.3×10−4 0.10

Kaur et al.

Kaur et al. BMC Bioinformatics 2012 13:191   doi:10.1186/1471-2105-13-191

Open Data