|Assignments of the entities enzyme (E), substrate (S) and product (P) for a sample sentence|
The ten assignments of E, S and P for the sentence “L-Arabinose isomerase catalyzes the conversion of L-arabinose to L-ribulose, the first step in the utilization of n-arabinose by Escherichia coli B/r”. Given that L-Arabinose isomerase is the only tagged protein, it is deemed to be the enzyme in all cases, whereas different numbers and orderings of substrates and products are possible, given the presence of three tagged small molecules (L-arabinose, L-ribulose and n-arabinose). Note that other potential orderings (namely E-P-S-P and E-S-P-S) are not considered, as they are deemed highly unlikely to occur in practice.
Czarnecki et al.
Czarnecki et al. BMC Bioinformatics 2012 13:172 doi:10.1186/1471-2105-13-172