Multiple sequence alignment of selected representatives of DUS subfamilies. Sequences are denoted by species’ name (six-letter abbreviation for genus or species e.g. Bacsub for B. subtilis), followed by protein name (if assigned) or the PDB code or NCBI Gene Identification (GI) number. The variable termini and non-conserved insertions are not shown; the number of omitted residues is indicated in parentheses. Secondary structure elements observed in the crystal structure of TM0096 (PDB code 1vhn) are shown under the group alignment as tubes (helices) and arrows (strands). Invariant and conserved residues are highlighted in black and grey, respectively. The potential catalytic residues are indicated by an asterisk (“*”).
Kasprzak et al. BMC Bioinformatics 2012 13:153 doi:10.1186/1471-2105-13-153