Maximum likelihood estimation of the position of pause sites. Logarithmic relative Likelihood for three models: Model C (left), model B (middle) and model D (right). The estimated maximum likelihood values of the nucleotide positions are 200, 410 and 780 (vertical blue lines) and the true position values (250, 500 and 750) are indicated by vertical green lines. The boundary of the 95% bootstrap confidence region of the ML estimates is indicated by horizontal lines.
Emmert-Streib et al. BMC Bioinformatics 2012 13:152 doi:10.1186/1471-2105-13-152