Figure 7.

Comparison of EMIM and LEM for Case/Parent Trios. Plots showing the comparison of EMIM and LEM using simulated data for 4000 case/parent trios, assuming R1=1.5 and R2=2.25 at SNP number 1004 and S1=2 and S2=3 at SNP number 6004. Plots of the <a onClick="popup('http://www.biomedcentral.com/1471-2105/13/149/mathml/M13','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1471-2105/13/149/mathml/M13">View MathML</a> p-values for each SNP to detect maternal effects given child and imprinting effects by: A: EMIM and B: LEM. Plots of the <a onClick="popup('http://www.biomedcentral.com/1471-2105/13/149/mathml/M14','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1471-2105/13/149/mathml/M14">View MathML</a> parameters values for: C: R1; D: R2; E: S1; F: S2; G: Im. H: Plot of the <a onClick="popup('http://www.biomedcentral.com/1471-2105/13/149/mathml/M15','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1471-2105/13/149/mathml/M15">View MathML</a> p-values for the alternative (5-parameter) model versus the null (3-parameter) model calculated using EMIM and MENDEL.

Howey and Cordell BMC Bioinformatics 2012 13:149   doi:10.1186/1471-2105-13-149
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