Comparison of EMIM and LEM for Child/Mother Duos. Plots showing the comparison of EMIM and LEM using simulated data for 2000 case/mother duos and 2000 control/mother duos, assuming R1=1.5 and R2=2.25 at SNP number 1000 and S1=2 and S2=3 at SNP number 6004. Plots of the p-values for each SNP to detect child and maternal effects by: A: EMIM and B: LEM. Plots of the parameters values for: C: R1; D: R2; E: S1and F: S2. G: Plot of the p-values for the alternative versus the null model calculated using EMIM and MENDEL.
Howey and Cordell BMC Bioinformatics 2012 13:149 doi:10.1186/1471-2105-13-149