Figure 3.

Results obtained by PIN, PAC, BMI and gene biomarkers on four lung cancer datasets. The biomarkers identified from lung cancer dataset (GSE 4115) by four methods were applied to independent lung cancer test datasets (GSE7670, GSE10072, GSE19027, and GSE2514), where PIN, PAC, BMI and Gene respectively denotes our pathway biomarkers, PAC biomarkers, BMI biomarkers and gene biomarkers. (A). GSE2514 dataset, where PIN gets AUC score of 0.99 compared with 0.99 by PAC, 0.95 by BMI and 0.87 by Gene. (B). GSE7670 dataset, where PIN gets AUC score of 0.99 compared with 0.99 by PAC, 0.80 by BMI and 0.85 by Gene. (C). GSE10072 dataset, where PIN gets AUC score of 0.99 compared with 0.99 by PAC, 0.93 by BMI and 0.96 by Gene. (D). GSE19027 dataset, where PIN gets AUC score of 0.71 compared with 0.63 by PAC, 0.65 by BMI and 0.52 by Gene.

Liu et al. BMC Bioinformatics 2012 13:126   doi:10.1186/1471-2105-13-126
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