Table 3

Adjusted relevance parameters
Edge type Source databases Relevance (interactions) Relevance (disease genes)
Article references All 4.0 1.0
Gene locations Entrez, OMIM 0.5
Gene affects Phenotype Entrez 5.0
GO annotations Entrez, Uniprot 1.0 0.5
OMIM references OMIM 0.25 1.0
Protein associations STRING 3.0 1.0
Protein interactions Entrez, UniProt 1.0 0.5
Pathway memberships KEGG 1.0
Gene-protein relations KEGG 10.0 10.0

Value “–” indicates that adjusting the relevance of the edge type did not have a clear effect on accuracy.

Eronen and Toivonen

Eronen and Toivonen BMC Bioinformatics 2012 13:119   doi:10.1186/1471-2105-13-119

Open Data