Sodium equivalence computation. MELTING uses a default formula to compute a sodium equivalent concentration (this figure illustrates an example of the formula from von Ahsen et al.). This sodium equivalent concentration is then used by the sodium correction formula to modify the melting temperature calculated. This sodium correction can be included into approximative formulae or can be a separate formula applied during the Nearest-Neighbor computation. Users can overide the default formula and enter values for sodium, potassium or magnesium ion species.
Dumousseau et al. BMC Bioinformatics 2012 13:101 doi:10.1186/1471-2105-13-101