Table 1

Overview of the responsive networks.

Network

#Genes

#Interactions

#DEGs*

#Hub interactions


Normal- cirrhosis

55

67

53 (96.3%)

42 (62.7%)

Cirrhosis- dysplasia

38

50

37 (97.4%)

35 (70.0%)

Dysplasia -early HCC

60

65

53 (88.3%)

37 (56.9%)

Early- advanced HCC

68

98

59 (86.8%)

79 (80.6%)


*Differentially expressed genes (DEGs) were identified as genes with up or down regulation fold change ≥ 2 and student t test P value ≤ 0.01.

Hub interaction number refers to the total number of interactions involving hub genes.

Hub genes were defined to have at least 5 interactions in each network.

Zheng and Zhao BMC Bioinformatics 2011 12(Suppl 7):A4   doi:10.1186/1471-2105-12-S7-A4

Open Data