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## Figure 6.
GOEAST analysis in biological process category of T1D study. The GOEAST graphical output of enriched GO terms in the biological process category
for our selected gene network of T1D study. Boxes represent GO terms, labeled by its
GO ID, term definition, and detailed information, organized as “q/m|t/k(p – value)”, where q is the count of genes associated with the listed GOID (directly or indirectly) in
our dataset, m is the count of genes associated with the listed GOID (directly or indirectly) on
the chosen platform, k is the total number of genes in our dataset, t is the total number of genes on the chosen platform, p-value is of the significance for the enrichment in the dataset of the listed GOID
under hypergeometric distribution. Significantly enriched GO terms are marked yellow.
The degree of color saturation of each node is positively correlated with the enrichment
significance of the corresponding GO term. Nonsignificant GO terms within the hierarchical
tree are shown as white boxes. Branches of the GO hierarchical tree without significantly
enriched GO terms are not shown. Arrows represent connections between different GO
terms. Red arrows represent relationships between two enriched GO terms, black solid
arrows represent relationships between enriched and unenriched terms and black dashed
arrows represent relationships between two unenriched GO terms.
Liu |