Table 1

Performances of the sequence (SVM-SEQ) and structure (SVM-3D) based methods.

Q2

P[D]

S[D]

P[N]

S[D]

C

AUC


SVM-SEQ

0.82

0.81

0.83

0.82

0.81

0.64

0.89

SVM-3D

0.85

0.84

0.87

0.86

0.83

0.70

0.92


The accuracy measures are defined in Methods section. D and N are disease-related and neutral variants respectively. Methods are tested on the B3D dataset.

Capriotti and Altman BMC Bioinformatics 2011 12(Suppl 4):S3   doi:10.1186/1471-2105-12-S4-S3

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