Discovery rate and true call rate. (A) Discovery rate is the mean of each ratio of overlapped region in the real SV between the real SV and the called SV determined by formula (2). In this case, the discovery rate is calculated as 0.797. When discovery rate is high, the number of true positive will increase. Thus, this discovery rate can be regarded as the similar concept to sensitivity. (B) True call ratio is the mean of each ratio of overlapped region in the called SV between the real SV and the called SV determined by formula (3). The true call rate is calculated as 0.833. When true call ratio is high, false positive will decrease. Thus, this true call ratio can be regarded as the similar concept to specificity.
Suzuki et al. BMC Bioinformatics 2011 12(Suppl 14):S7 doi:10.1186/1471-2105-12-S14-S7