Open Access Highly Accessed Methodology article

Learning genetic epistasis using Bayesian network scoring criteria

Xia Jiang1*, Richard E Neapolitan5, M Michael Barmada4 and Shyam Visweswaran123

Author Affiliations

1 Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA

2 Intelligent Systems Program, University of Pittsburgh, Pittsburgh, PA, USA

3 Clinical and Translational Science Institute, University Pittsburgh, Pittsburgh, PA, USA

4 Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA

5 Department of Computer Science, Northeastern Illinois University, Chicago, IL, USA

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BMC Bioinformatics 2011, 12:89  doi:10.1186/1471-2105-12-89

Published: 31 March 2011

Additional files

Additional file 1:

Illustrative Example of Better Large α Performance. This file provides an illustrative example to demonstrate a possible explanation for the better performance of the BDeu score at larger values of α on hard-to-detect genetic models.

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