Pairwise phenotypic distance vs. pairwise genotypic distance for all pairs of sequences. (a) Scaled phenotypic distance vs. genotypic distance with all positions considered in calculating genotypic distance and (b) with only resistance-associated positions used in calculating genotypic distance. The density of points is colored according to the scale at right. The sequence pairs corresponding to two points are indicated. The 9-digit shorthand used to describe the two pairs of sequences indicates the resistance score (Table 2) to the PIs in the order used in Fig. 1: RTV, NFV, ATV, APV, IDV, LPV, SQV, TPV, DRV.
Doherty et al. BMC Bioinformatics 2011 12:477 doi:10.1186/1471-2105-12-477