Additional file 1.

Table S1.1 OTU counts. J-C: Jukes-Cantor; 50 × 60 seq mut inter: 50 mutated copies of the 60 sequences dataset interleaved; 50 × 60 seq mut stack: 50 mutated copies of the 60 sequences dataset stacked; NC: not computable; t1, t2: samples taken at time 1 or time 2 (see Methods). Values marked with an * were computed using only unique sequences. Table S1.2 ACE estimates J-C: Jukes-Cantor; 50 × 60 seq mut inter: 50 mutated copies of the 60 sequences dataset interleaved; 50 × 60 seq mut stack: 50 mutated copies of the 60 sequences dataset stacked; NC: not computable; t1, t2: samples taken at time 1 or time 2 (see Methods). Values marked with an * were computed using only unique sequences. CROP, Outpipe and RDP does not compute the ACE estimator. Table S1.3 Chao1 estimates J-C: Jukes-Cantor; 50 × 60 seq mut inter: 50 mutated copies of the 60 sequences dataset interleaved; 50 × 60 seq mut stack: 50 mutated copies of the 60 sequences dataset stacked; NC: not computable; t1, t2: samples taken at time 1 or time 2 (see Methods). Values marked with an * were computed using only unique sequences. CROP and Outpipe does not compute the Chao1 estimator.

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Barriuso et al. BMC Bioinformatics 2011 12:473   doi:10.1186/1471-2105-12-473