Table 3

Change of ranking when using the modified Gumbel distribution

FQPS λ2 = 0

FQPS λ2 ≠ 0

Query

rank

Subject

LS

p-value

rank

Subject

LS

p-value


P08100

433

Q90456

287

1.1 × 10 -21

445

Q8N6U8

529

7.2 × 10 -29

LQ = 348

476

Q8N6U8

529

2.1 × 10 -21

483

Q90456

287

2.1 × 10 -28


P50052

79

P32250

308

1.1 × 10 -37

64

P34975

380

1.2 × 10 -57

LQ = 363

100

P34975

380

1.8 × 10 -37

111

P32250

308

1.3 × 10 -56


Q18179

772

P18901

446

2.2 × 10 -21

790

P79291

228

9.2 × 10 -27

LQ = 455

837

P79291

228

1.1 × 10 -20

794

P18901

446

9.8 × 10 -27


P35348

825

Q8HYN8

297

9.8 × 10 -24

826

O70432

167

5.2 × 10 -30

LQ = 466

937

O70432

167

1.3 × 10 -21

847

Q8HYN8

297

1.9 × 10 -29


Examples of blast hits for the four proteins used for FQPS. The original result sets have been re-ranked according the the FQPS statistics. Left column: Gumbel assumption (λ2 = 0). Right column: Modified Gumbel distribution (λ2 ≠ 0).

Wolfsheimer et al. BMC Bioinformatics 2011 12:47   doi:10.1186/1471-2105-12-47

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