Table 2

Enriched functional categories according to DAVID analysis, related to Figure 2C.

Network Cluster No.

No. Enriched Proteins (total)

Functional Category

Enrichment Score

Benjamini P-value


1

76 (483)

pattern specification process

34.7

8.3 × 10-43

32 (483)

lung development

25.1

1.3 × 10-18

55 (483)

blood vessel development

22.0

8.3 × 10-27

71 (483)

skeletal system development

21.1

6.8 × 10-38

32 (483)

gland morphogenesis

17.3

1.6 × 10-22


2

61 (339)

immune system development

28.4

1.5 × 10-36

63 (339)

defense response

20.4

3.3 × 10-28


3

43 (182)

neuron projection

24.0

1.2 × 10-34

38 (182)

transmission of nerve impulse

14.8

1.4 × 10-27


4

57 (106)

DNA metabolic process

36.5

1.1 × 10-54

51 (106)

cell cycle

19.8

2.3 × 10-37


5

16 (65)

regulation of apoptosis

4.8

1.8 × 10-5

10 (65)

chaperone

4.4

2.2 × 10-7


6

12 (34)

cell motion

8.3

1.4 × 10-7

8 (34)

vasculature development

3.6

1.4 × 10-4


7

7 (24)

leukocyte differentiation

4.9

3.7 × 10-6

5 (24)

regulation of T cell activation

3.2

1.9 × 10-3


8

15 (21)

visual perception

12.3

4.5 × 10-19

9 (21)

eye development

9.4

4.2 × 10-10


9

0 (18)

no enrichment

NS

NS


10

8 (11)

DNA binding

4.7

9.9 × 10-4

6 (11)

chordate embryonic development

4.1

1.8 × 10-3


Morris et al. BMC Bioinformatics 2011 12:436   doi:10.1186/1471-2105-12-436

Open Data