Table 1

10 External ontologies used for the MPO test-run

Ontology

Number classes in Ontology

Fraction of terms referenced in logical definitions

Chemical Entities of Biological Interest

44,843

2.71 %

Gene Ontology

35,090

4.35 %

Protein Ontology

26,727

0.18 %

Molecule Role Ontology

9,530

0.66 %

Uber-Anatomy (UBERON)

8,111

17.70 %

BRENDA Tissue Ontology

4,975

0.28 %

Adult Mouse Anatomical Dictionary

2,994

43.05 %

Phenotype, Attribute and Trait Ontology

2,283

23.87 %

Cell Ontology

1,510

30.20 %

Mouse Pathology

643

18.97 %

Total

140,453

7.45 %

Less than 10 % of the terms of the external ontologies are used by the logical definitions of the MPO terms. "Fraction of terms referenced in logical definitions" denotes the percentage of terms in the ontology that are members of the induced ancestral graph and are used by the logical definitions of the MPO terms.

Köhler et al. BMC Bioinformatics 2011 12:418   doi:10.1186/1471-2105-12-418