Comparison of the NDFs computed with deterministic versus stochastic reactions. NDFs computed with deterministic dynamics are marked as "Deter. Rxn" whereas the ones with stochastic reaction occurrence are marked as "Stoch. Rxn". For all deterministic simulations, the cell population was initiated with 20 cells and Ncellsmax = 104. For all stochastic simulations batches of 20 simulations were run with Ncellsmax = 500. In all cases sampling was performed at t = 300 min. Panel (a): [Iex] = 10 μM. Panel (b): [Iex] = 24 μM. Panel (c): [Iex] = 50 μM. All other parameters as in Table 3.
Stamatakis and Zygourakis BMC Bioinformatics 2011 12:301 doi:10.1186/1471-2105-12-301