GPS-Prot: a web-based platform for visualizing diverse HIV-host data. (A) GPS-Prot homepage. Searches are initiated by selecting databases and an HIV or host protein. (B) A Touchgraph Navigator window is launched to display results of a search, which contains the protein interaction network. Single clicking any interaction ("edge", or gray line connecting proteins) provides the evidence from the literature for that interaction in the left-hand panel. Clicking on any protein in the diagram ("node") pulls up details for that protein (e.g. panel labeled CUL5). There is also a searchable table that can be sorted by score, database or experiment. A new network can be created by double clicking any protein (node), thus, it is possible to "walk through" the entire HIV-human or human-human interactome.
Fahey et al. BMC Bioinformatics 2011 12:298 doi:10.1186/1471-2105-12-298