Distribution of allele frequencies of SNPs simulated assuming the standard stationary distribution of allele frequencies. At each depth (each panel), 20,000 SNPs were simulated, and for each SNP, estimates of the MAF were obtained using four different methods (see the caption of Figure 1). Then, for each method (each color), only sites with estimated allele frequencies > 2% are used to generate each histogram (x-axis).
Kim et al. BMC Bioinformatics 2011 12:231 doi:10.1186/1471-2105-12-231