Table 6

Top ranking co-occurring domains in high confidence binding sites from yeast.

Domain Name A

Domain Name B

DOMINE


Src homology-3 domain

Src homology-3 domain

Known

Src homology-3 domain

Uncharacterised conserved protein UCP037464, actin patch protein 1

Novel

Src homology-3 domain

Adenylate cyclase-associated CAP, N-terminal

Known

Src homology-3 domain

EF-Hand 1, calcium-binding site

Novel

Src homology-3 domain

Protein of unknown function DUF3210

Known

Src homology-3 domain

BTB/POZ fold

Novel

Src homology-3 domain

Septin

Known

Src homology-3 domain

C2 calcium/lipid-binding domain, CaLB

Novel

Src homology-3 domain

Serine/threonine-protein kinase-like domain

Known

Homeobox

Transcription factor, MADS-box

Known


Binding sites included in this analysis had DM ≤ 0.20. Among interacting domain pairs in all sites, 10 out of 15 (66.7%) pairs are reported in the DOMINE database

Amos-Binks et al. BMC Bioinformatics 2011 12:225   doi:10.1186/1471-2105-12-225

Open Data