BMC Bioinformatics

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Open Access Highly Access Software

BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets

Mark J Alston1,4*, John Seers2, Jay CD Hinton1,5 and Sacha Lucchini3

Author Affiliations

1 Foodborne Bacterial Pathogens, Institute of Food Research, Norwich Research Park, Norwich, NR4 7UA, UK

2 Bioinformatics & Statistics, Institute of Food Research, Norwich Research Park, Norwich, NR4 7UA, UK

3 Integrated Biology of the GI Tract, Institute of Food Research, Norwich Research Park, Norwich, NR4 7UA, UK

4 Current address: The Genome Analysis Centre, Norwich Research Park, Norwich, NR4 7UH, UK

5 Current address: Department of Microbiology, Moyne Institute of Preventive Medicine, School of Genetics and Microbiology, Trinity College, Dublin 2, Ireland

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BMC Bioinformatics 2010, 11:73 doi:10.1186/1471-2105-11-73

Published: 3 February 2010

Additional files

Additional file 1:

BABAR software. The BABAR R package.

Format: ZIP Size: 40KB Download file

Open Data

Additional file 2:

BABAR documentation. Vignette detailing the installation and running of BABAR.

Format: PDF Size: 390KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

Dataset 1. The unprocessed microarray data files from a heterogeneous 'problem' dataset describing the transcriptomic changes for Salmonella internalised within mammalian cells.

Format: ZIP Size: 8.5MB Download file

Open Data

Additional file 4:

Dataset 2. The unprocessed microarray data files and the associated .gal file for a non-heterogeneous 'good' dataset describing the transcriptomic changes of virulence genes for wild-type Salmonella and IHF mutants.

Format: ZIP Size: 13.1MB Download file

Open Data